Bradykinin Is a Nonapeptide Released by Globulins in the Blood

question 26

Short Answer

Bradykinin is a nonapeptide released by globulins in the blood in response to a wasp sting. Hydrolysis gives the following amino acids: 2 Arg, Gly, 2 Phe, 3 Pro, and Ser. Edman degradation gives phenylthiohydantoin of Arg. Cleavage with carboxypeptidase gives Arg. Partial hydrolysis gives the following di- and tripeptides: Phe-Ser, Pro-Gly-Phe, Pro-Pro, Ser-Pro-Phe, Phe-Arg, and Arg-Pro. What is the amino acid sequence of bradykinin?

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Definitions:

Aboveground

Pertaining to or situated on the surface of the earth; not underground or underwater.

Sexual Spore

A reproductive structure in fungi and some plants formed by the fusion of two distinct parent cells, leading to genetic recombination and variation.

Club-Shaped

A term describing an object, organ, or structure that is broader or round at one end and tapers towards the other end, similar to the shape of a club.

Basidia

Specialized spore-producing cells found in the reproductive structures of basidiomycete fungi.