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Describe the significance of resonance structures in understanding the stability of intermediates in electrophilic aromatic substitution reactions.
Explain the rate-determining step in electrophilic aromatic substitution reactions.
Demonstrate the ability to predict the reactivity of different aromatic compounds towards electrophilic substitution reactions.
Sketch mechanisms for electrophilic aromatic substitution reactions based on given reactants.

Definitions:

Secondary Intention

Wound healing that occurs by granulation, contraction, and epithelialization, often used for wounds that cannot be closed by primary intention.

Deep Pressure Ulcers

Severe injuries to the skin and underlying tissue resulting from prolonged pressure on the skin.

Infected Wounds

Refers to wounds that have been contaminated with pathogenic microorganisms, leading to infection characterized by redness, pain, warmth, and possibly discharges.

Primary Dressing

The first layer of dressing applied directly to a wound, designed to come in contact with the wound surface.

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