The Mechanisms Underlying the Development of Cardiac Hypertrophy Are Complex,although

question 3

Multiple Choice

The mechanisms underlying the development of cardiac hypertrophy are complex,although relaxation abnormalities that result in chronic elevation of cytosolic Ca⁺⁺ level appear to promote the development of hypertrophy through:

• A)Stimulation of the sarcolemmal Ca⁺⁺ pump.
• B)Ca⁺⁺ binding to troponin I.
• C)Activation of calcineurin.
• D)Inhibition of Ca⁺⁺/calmodulin-dependent protein kinase.
• E)Opening of Ca⁺⁺-activated K⁺ channels.

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