Why Would Co-Administration of a Bacteriostatic Drug Interfere with the Effects

question 37

Multiple Choice

Why would co-administration of a bacteriostatic drug interfere with the effects of penicillin?

• A)Since most bacteriostatic drugs are produced from bacteria,but penicillin is produced from mold,the two drugs are incompatible with each other.
• B)A bacteriostatic drug produces interference in the ability of a bacterial cell to take in compounds from the outside environment.Penicillin must be taken in by the cell in order to have its effect,so this would directly inhibit it.
• C)Penicillin interferes with cell wall production/stabilization by cross-linking of peptidoglycan.As such,it only works when the cells are actively replicating and MAKING new peptidoglycan.A bacteriostatic drug works by shutting down replication,holding the cells "static." This would interfere with the mode of action required by the penicillin.
• D)The bacteriostatic drugs would bind directly to the penicillin,preventing both its uptake by the cell and its ability to perform its duty within the bacterial cell.

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