Because of the structure of the RNA sugar-phosphate backbone,RNA is subject to base-promoted hydrolysis,as shown below.Suggest a mechanism for base-promoted RNA hydrolysis. 
Definitions:
Material Resources
Physical or tangible assets that can be used to produce goods and services, including natural resources, buildings, machinery, and tools.
Laissez-faire Leadership
A leadership style characterized by minimal intervention in the affairs of others, allowing people to act according to their own preferences.
Subordinates
Individuals or groups who are lower in rank, position, or authority within a hierarchy.
Direction
Can refer to guidance or supervision towards achieving a goal or to the specific path that something or someone moves or is aimed toward.
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