Which Statement Regarding Pharmacokinetic Changes in the Elderly Is True

question 18

Multiple Choice

Which statement regarding pharmacokinetic changes in the elderly is true?

• A)Hypoalbuminemia can increase drug effects by increasing the amount of free drug.
• B)Elderly patients experience no change in first-pass effect.
• C)Liver size and blood flow are not affected by age.
• D)Phase I and phase II metabolism are not affected by age in normal patients.

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Definitions:

SSE

Stands for Sum of Squares due to Error, a measure in statistics used to quantify the discrepancy between the data and an estimation model.

Regression Hyperplane

In multivariate linear regression, a flat surface that best fits the data points in a multi-dimensional space, generalizing the concept of a regression line.

Independent Variables

Variables in an experiment or model that are manipulated or categorized to determine their effect on dependent variables.

Squared Vertical Deviations

Squared vertical deviations represent the square of differences between observed values and their means in a data set, often used in regression analysis to measure dispersion.