Which Option Describes the Mechanism of Action of PIs

question 34

Multiple Choice

Which option describes the mechanism of action of PIs?

• A)Bind to an active site used by viral protease enzymes so they cannot process viral precursors critical to the maturation of HIV virus
• B)Bind to the active site of HIV reverse transcriptase and their antiviral activity is additive or synergistic with most other antiretrovirals
• C)Convert to active compounds in the presence of host enzymes,becoming part of the DNA chain,where they interfere with DNA synthesis and viral replication through their inhibition of viral RNA
• D)Compete with natural nucleotides in the host that would otherwise be incorporated into the newly synthesized DNA copies of the HIV virus;therefore,inhibit viral growth by terminating the virus' DNA chain

Realize the importance of validation techniques such as item analysis, content analysis, and expert consultation.

Understand the role of validity (convergent, discriminant, empirical) in the context of scale development and the methods for establishing it.

Recognize the necessity of cross-cultural validation processes for scales intended for use in different cultural contexts.

Grasp the fundamental aim of factor analysis in identifying underlying psychological constructs.

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Definitions:

Calibrated Spoon

A spoon that has special markings, or calibrations, that allow you to measure a dose of liquid medication.

Pediatric Patients

children and adolescents who are receiving medical treatment or care.

Oral Medications

Medicines taken by mouth to be absorbed through the digestive system, used to treat a wide range of illnesses and conditions.

Topical Application

The act of applying a substance directly onto a particular area of the skin or mucous membranes for local effect.