COX-1-Inhibiting NSAIDs Result in Adverse Effects on the Gastrointestinal Tract

question 34

Multiple Choice

COX-1-inhibiting NSAIDs result in adverse effects on the gastrointestinal tract.What causes this adverse effect?

• A)COX-1 regulates gastric acid secretion.
• B)COX-1 inhibits the synthesis of prostaglandins.
• C)COX-1 regulates endothelial cells in the kidney.
• D)COX-1 promotes the secretion of histamine.

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Definitions:

Epiphyseal Plate

A hyaline cartilage plate in the long bones, where lengthwise growth of the bone occurs.

Ossified

The process by which tissue turns into bone or a bony substance, often part of normal bone growth and development or healing of fractures.

Hypersecretion

The excessive production and release of substances, such as hormones or enzymes, by a gland or organ.

Adrenal Tumor

A growth, either benign or malignant, that forms in the adrenal glands, which are located above the kidneys and are responsible for hormone production, including stress hormones and sex hormones.