Clonal Libraries Used to Determine the Sequence of a Microbial

question 59

Multiple Choice

Clonal libraries used to determine the sequence of a microbial genome using the whole-genome shotgun approach are typically generated by

• A)cloning small gene sized DNA fragments produced by breaking chromosomal DNA with ultrasonic waves.
• B)cloning large DNA fragments produced by breaking chromosomal DNA with ultrasonic waves.
• C)cloning random PCR fragments amplified from genomic DNA.
• D)cloning large DNA fragments produced by restriction endonuclease cleavage.

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