Curare Is a Poison Used by South American Indians

question 21

Multiple Choice

Curare is a poison used by South American Indians. It is known to bind to ACh receptors preventing the binding of ACh. What effect would it have on muscle function?

• A) The muscle fibers would contract uncontrollably and continually.
• B) The muscle fibers would not contract because the Na⁺ channels which cause depolarization of the muscle fiber membrane are never signaled to open.
• C) The pre-synaptic release of ACh would be inhibited, therefore the muscle would not contract.
• D) The action of acetylcholinesterase would be inhibited causing increased contraction.
• E) Both the muscle fibers would contract uncontrollably and continually and the action of acetylcholinesterase would be inhibited causing increased contraction would occur.

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