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Scenario I
The following scenario is based on and presents fabricated data consistent with the following study:
Caspi,A. ,Sugden,K. ,Moffitt,T.E. ,Taylor,A. ,Craig,I.W. ,Harrington,H. ,McClay,J. ,Mill,J. ,Martin,J. ,Braithwaite,A. ,and Poulton,R.(2003) .Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene.Science,301(5631) ,386-389.
The serotonin transporter gene codes for the serotonin transporter,a protein that transports serotonin from the synapse to the presynaptic neuron.Several polymorphisms of the gene exist,including a "short" (s) and a "long" (l) variation.As humans receive one copy of the gene from each parent,people can be grouped into three groups based on this genetic variation: s/s (two copies of the short gene) ,s/l,and l/l.Caspi et al.(2003) interviewed participants in each of these groups and asked them a wide range of questions to determine both the degree of exposure to stress and the number of depressive episodes participants had experienced in their lives.Fabricated results consistent with their major findings are shown in Figure 3.1.
Figure 3.1
-(Scenario I) An individual has two copies of the small variation of the serotonin transporter gene and has been exposed to a high degree of stress over the course of her lifetime.Based on the results shown in the scenario,one could:
Conscientious
Characterized by carefulness, diligence, and a desire to do a task well.
Defensive
Relating to a behavior or mindset aimed at protecting oneself from criticism, harm, or other perceived threats.
Extraverted
Extraverted describes a personality trait characterized by outgoingness, sociability, and a preference for external stimulation over introspection.
Intelligent
The ability to learn, understand, and apply knowledge, solve problems, and adapt to new situations.
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