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In December 2010,approximately 6000 male mosquitoes were released in Malaysia.They contained a fruit fly gene called "tTA," which kills the mosquito when expressed.In the lab,tTA gene expression was suppressed by treating the mosquitos with tetracycline.The goal for releasing the males was to allow them to mate with wild female mosquitoes.The resulting offspring from this mating would all die,and the number of mosquitoes in the area would plummet,as would the number of humans infected by dengue fever through mosquito bites.The released male mosquitos would then also die from lack of tetracycline-based suppression of tTA gene expression.
In the male mosquitoes,tTA is


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