When a Polypeptide Is in Its Native Conformation, There Are

question 51

Short Answer

When a polypeptide is in its native conformation, there are weak interactions between its R groups. However, when it is denatured there are similar interactions between the protein groups and water. What then accounts for the greater stability of the native conformation?

---

Definitions:

Buffer

A solution or substance that minimizes changes in pH by absorbing or releasing hydrogen ions.

Acidic

Describes substances with a pH less than 7, characterized by a higher concentration of hydrogen ions.

Neutralize

To render something harmless by applying an opposite force or effect, such as neutralizing an acid with a base.

Denature

The process by which a protein loses its three-dimensional structure due to external stress or compounds, affecting its functionality.