The Function of the Eukaryotic DNA Replication Factor PCNA (Proliferating $\beta$

question 83

Multiple Choice

The function of the eukaryotic DNA replication factor PCNA (proliferating cell nuclear antigen) is similar to that of the $\beta$ subunit of bacterial DNA polymerase III in that it:

• A) facilitates replication of telomeres.
• B) forms a circular sliding clamp to increase the processivity of replication.
• C) has a 3ʹ\(\rightarrow\) 5ʹ proofreading activity.
• D) increases the speed but not the processivity of the replication complex.
• E) participates in DNA repair.

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Definitions:

Bleed Screw

A small valve or screw located on hydraulic systems, such as brakes, used to remove air from the system.

Relay Valve

A valve used in air brake systems that speeds up the application and release of brakes over long distances by shortening the response time.

Primary Circuit

The initial or main electrical circuit in a system, responsible for providing the primary flow of electricity or the initial path for the current.

Secondary Circuit

An auxiliary or supplementary electrical circuit that operates alongside or in addition to the main circuit, often for distinct or specialized tasks.