In Comparing Fatty Acid Biosynthesis With $\beta$ Oxidation of Fatty Acids,which of the Following Statements Is Incorrect

question 19

Multiple Choice

In comparing fatty acid biosynthesis with $\beta$ oxidation of fatty acids,which of the following statements is incorrect?

• A)A thioester derivative of crotonic acid (trans-2-butenoic acid)is an intermediate in the synthetic path,but not in the degradative path.
• B)A thioester derivative of D-\(\beta\)-hydroxybutyrate is an intermediate in the synthetic path,not in the degradative path.
• C)Fatty acid biosynthesis uses NADPH exclusively,whereas \(\beta\) oxidation uses NAD⁺ exclusively.
• D)Fatty acid degradation is catalyzed by cytosolic enzymes;fatty acid synthesis by mitochondrial enzymes.
• E)The condensation of two moles of acetyl-CoA in the presence of a crude extract is more rapid in bicarbonate buffer than in phosphate buffer at the same pH;the cleavage of acetoacetyl-CoA proceeds equally well in either buffer.

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