Preparation of an Extract of Muscle Results in a Dramatic

question 31

Essay

Preparation of an extract of muscle results in a dramatic decrease in the concentration of citric acid cycle intermediates compared to their concentrations in the tissue. However, in 1935, Szent-Gyorgi showed that the production of CO₂ by the extract increased when succinate was added. In fact, for every mole of succinate added, many extra moles of CO₂ were produced. Explain this effect in terms of the known catabolic pathways.

---

Definitions:

Break-Even Sales

The amount of revenue required to cover the total fixed and variable costs of a business.

Contribution Margin

The difference between the sales revenue of a company and its variable costs, indicating how much contributes to covering its fixed costs and generating profit.

Sales Volume

The total quantity of sales or units sold within a particular time frame.

Break-Even Point

The point at which total costs equal total revenues, meaning the business is not making a profit or a loss.