Which of the Following Is Not True for G Protein-Coupled

question 50

Multiple Choice

Which of the following is not true for G protein-coupled receptors (GPCRs) ?

• A)Agonists mimic the effect of the natural ligand.
• B)Antagonists block the normal effect of the natural ligand.
• C)GPCRs interact with heterodimeric G proteins.
• D)GPCRs are have seven transmembrane helices.
• E)There exist >100 orphan GPCRs in the human genome with no known ligand.

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