Mutations in Which of the Following Are Not Part of the Progression

question 66

Multiple Choice

Mutations in which of the following are not part of the progression from normal to cancerous cells in colorectal cancer?

• A)Abl involved in cellular signaling
• B)KRAS and BRAF kinases involved in cellular signaling
• C)PI3K and PTEN involved in cellular signaling
• D)MMR involved in DNA repair
• E)CDC4 involved in ubiquitination

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Definitions:

Markup Percentage

The percentage added to the cost of goods to cover overhead and profit, determining the selling price.

Factory Overhead

Costs associated with production that are not directly tied to individual products, including utilities, maintenance, and salaries of supervisory staff.

Activity-Based Costing

A costing method that assigns overhead and indirect costs to related products and services based on the amount of activities used to produce them.

Markup Percentage

The percentage added to the cost of goods to determine the selling price, reflecting the profit margin on sales.