Provide Examples Where Tumor Cells Transferred Between a Donor and a Recipient

Question

Examlex · Accepted Answer

The Answer is A. If primary tumor cells are donated between MHC-disparate mice, the cytotoxic T cells of the recipient recognize differences in MHC class I and kill the tumor cells.
B. (i) The marsupial known as the Tasmanian devil can pass tumor cells between individuals when fighting and biting each other’s faces. Because of limited MHC diversity in the species, there is a lack of allograft rejection, and the tumor cells establish themselves at the site of facial injury. (ii) In humans, residual tumor cells in an HLA-matched transplanted organ will not be rejected because the recipient is immunosuppressed and unable to mount an antitumor immune response.

Provide Examples Where Tumor Cells Transferred Between a Donor and a Recipient

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