Li-Fraumeni Syndrome Is Linked to a Greater Risk of Cancer

question 20

Multiple Choice

Li-Fraumeni syndrome is linked to a greater risk of cancer as a result of the inheritance of a germline mutation in one copy of _____.

• A)TLR-9
• B)p53
• C)CTLA4
• D)heat-shock protein
• E)Rb.

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Definitions:

Least Squares Method

A mathematical approach used to find the best-fitting line through a set of points by minimizing the sum of the squares of the offsets (residuals) between the observed and predicted values.

Scatter Diagram

A graphical representation using dots to show the relationship between two sets of data.

Regression Models

Statistical techniques used for modeling and analyzing the relationships between a dependent variable and one or more independent variables.

Residual

The difference between observed values and the values predicted by a model.