Individuals Who Have Two Defective Alleles of the AIRE Gene

question 40

Multiple Choice

Individuals who have two defective alleles of the AIRE gene _____.

• A)exhibit symptoms of autoimmunity at a young age
• B)are unable to activate regulatory T cells
• C)exhibit decreased predisposition to autoimmune disease
• D)are very effective at inducing anergy of circulating autoreactive B and T cells
• E)are more likely to be women of African or Asian origin.

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