Which of the Following Statements Regarding C1 Inhibitor (C1INH)is False

question 16

Multiple Choice

Which of the following statements regarding C1 inhibitor (C1INH) is false? (Select all that apply.)

• A)C1INH belongs to a family of serine and cysteine protease inhibitors called the serpins.
• B)C1INH inhibits C1r but not C1s,so partial serine protease activation is achieved in the classical complement pathway.
• C)C1INH is cleaved by C1.
• D)When bound to C1 as a pseudosubstrate,it activates the protease activity of C1.
• E)Heterozygous individuals who have a single-gene defect in C1INH cannot make sufficient quantities of the gene product and must receive recombinant C1INH by infusion.

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