ADeficiencies in Antibody Production Can Be Due to a Variety

question 75

Essay

A.Deficiencies in antibody production can be due to a variety of underlying genetic defects.Name two immunodeficiency diseases,other than the severe combined immunodeficiencies,in which a defect in antibody production is the cause of the disease,and for which the underlying genetic defect is known.For each disease,say (i)how antibody production is affected,and (ii)what the underlying defect is and why it has this effect.
B.What is the main clinical manifestation of immunodeficiency diseases in which antibody production is defective but cell-mediated immune responses are intact?

---

Definitions:

Tertiary

Referring to the third level or stage in a sequence, system, or hierarchy.

Tapped

In electrical engineering, refers to creating a connection point at some location along a wire or winding of a transformer to draw off voltage.

Autotransformer

A type of electrical transformer with a single winding that acts as both the primary and the secondary winding, used for varying the level of voltage.

Primary

The initial or most important in order of development or consideration.