What Is the Fate of Centrocytes in Which Somatic Hypermutation

question 58

Multiple Choice

What is the fate of centrocytes in which somatic hypermutation has resulted in high-affinity receptors for antigen? (Select all that apply.)

• A)They die by apoptosis.
• B)They express Bcl-x_L.
• C)They process antigen and present it to T_FH cells.
• D)CD40 on the centrocyte engages with CD40 ligand on T_FH cells.
• E)They undergo phagocytosis by tingible body macrophages.

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