The Release of Lytic Granules from Cytotoxic T Cells Is

question 45

Multiple Choice

The release of lytic granules from cytotoxic T cells is aimed specifically at infected target cells while preserving the integrity of neighboring,uninfected cells.This is best explained by the observation that _____.

• A)only target cells bearing appropriate peptide:MHC class I complexes are susceptible to necrosis
• B)redistribution of lytic granules in the T cell delivers them to confined areas on the target cell in contact with the T cell
• C)regulatory T cells deliver survival signals to uninfected neighboring cells that renders them resistant to cytotoxins
• D)the amount of cytotoxins in a given cytotoxic T cell is so limited that only the cell closest to the T cell will succumb to the effects of perforin and granzyme
• E)uninfected cells are highly resistant to the effects of cytotoxins.

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