Which of the Following Statements Regarding Positive Selection Is Correct

question 13

Multiple Choice

Which of the following statements regarding positive selection is correct?

• A)All subsets of developing T cells undergo positive selection before export to the peripheral circulation.
• B)T-cell receptor editing is linked to the process of positive selection.
• C)Positive selection results in the production of T cells bearing T-cell receptors that have the capacity to interact with all allotypes of MHC class I and class II molecules,and not just those of the individual.
• D)Positive selection ensures that autoreactive T cells are rendered non-responsive.
• E)If there is a genetic defect in AIRE,then T-cell development is arrested as positive selection commences.

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