Individuals Who Fail to Express Functional Bruton's Tyrosine Kinase Exhibit

question 22

Multiple Choice

Individuals who fail to express functional Bruton's tyrosine kinase exhibit all of the following characteristics except

• A)B-cell development is blocked at the immature B-cell stage.
• B)They are usually male because the Btk gene is on the X chromosome.
• C)They suffer from an immune deficiency known as X-linked agammaglobulinemia (XLA).
• D)Recurrent infections with extracellular bacteria are common.
• E)They benefit from treatment with immunoglobulin infusions.

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Definitions:

Extended Family

Multiple generations of adults living with their spouses and children.

Nuclear Family

A family unit consisting of two parents and their children living together as a single household.

Intimate Femicide

The killing of a woman by an intimate partner or ex-partner, a severe form of violence against women.

Aboriginal Ancestry

Refers to individuals or populations with lineage that can be traced back to the original inhabitants of a region, prior to colonization.