Identify Which of the Following Statements Is True Regarding the Transporter

question 78

Multiple Choice

Identify which of the following statements is true regarding the transporter associated with antigen processing (TAP) .

• A)TAP is a homodimer composed of two identical subunits.
• B)TAP transports proteasome-derived peptides from the cytosol directly to the lumen of the Golgi apparatus.
• C)TAP is an ATP-dependent,membrane-bound transporter.
• D)Peptides transported by TAP bind preferentially to MHC class II molecules.
• E)TAP deficiency causes a type of bare lymphocytes syndrome resulting in severely depleted levels of MHC class II molecules on the surface of antigen-presenting cells.

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