The Mechanisms Contributing to Peptide Editing Include Which of the Following

question 33

Multiple Choice

The mechanisms contributing to peptide editing include which of the following? (Select all that apply.)

• A)removal of amino acids from the amino-terminal end by endoplasmic reticulum aminopeptidase (ERAP)
• B)cathepsin S-mediated cleavage of invariant chain
• C)the participation of tapasin in finding a 'good fit' for class I heterodimers
• D)recycling an MHC class I heterodimer if the peptide falls out of its peptide-binding groove
• E)upregulation of HLA-DM by interferon-γ.