Which Is the Most Likely Reason That HIV-Infected People with Heterozygous

question 12

Multiple Choice

Which is the most likely reason that HIV-infected people with heterozygous HLA loci have a delayed progression to AIDS compared with patients who are homozygous at one or more HLA loci?

• A)The greater number of HLA alleles provides a wider variety of HLA molecules for presenting HIV-derived peptides to CD8 T cells even if HIV mutates during the course of infection.
• B)Heterozygotes have more opportunity for interallelic conversion and can therefore express larger numbers of MHC alleles.
• C)Directional selection mechanisms favor heterozygotes and provide selective advantage to pathogen exposure.
• D)As heterozygosity increases,so does the concentration of alloantibodies in the serum,some of which cross-react with and neutralize HIV.

---

Definitions:

Prices

The amount of money required to purchase a good, service, or asset, often influenced by supply and demand.

Short-run

A period in which at least one factor of production is fixed, limiting the ability of a business to fully adjust to market changes.

Short-run Aggregate Supply

The total supply of goods and services that firms in an economy plan on selling during a specific time period at current prices.

Short-run Phillips Curve

It illustrates the inverse relationship between the rate of inflation and the unemployment rate in the short term.