Peptides That Bind to a Particular MHC Isoform Usually Have

question 61

Multiple Choice

Peptides that bind to a particular MHC isoform usually have either the same or chemically similar amino acids at two to three key positions that hold the peptide tightly in the peptide-binding groove of the MHC molecule.These amino acids are called _____ and the combination of these key residues is known as its _____.

• A)alleles; allotypes
• B)anchor residues; peptide-binding motif
• C)allotype; haplotypes
• D)invariant chains; haplotypes
• E)restriction residues; MHC allotype.

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Definitions:

Double-ovulate

The occurrence of releasing two eggs during a single menstrual cycle, which can lead to fraternal twins if both eggs are fertilized.

X-linked

A term referring to genes or genetic conditions that are associated with the X chromosome, often affecting males more frequently or severely because they have only one X chromosome.

Dominant-recessive

describes a genetic pattern in which one allele overshadows the effects of another, recessive allele in determining a trait's appearance.

Additive Genes

Genes that each contribute to the characteristic—they “add up” rather than one being hidden (recessive). For example, skin color is additive: It shows the combined genes of both parents, rather than taking after one or the other.