(I)Describe the Structure of an MHC Class I Molecule,identifying the Different

question 82

Essay

(i)Describe the structure of an MHC class I molecule,identifying the different polypeptide chains and domains.(ii)What are the names of the MHC class I molecules produced by humans? Which part of the molecule is encoded within the MHC region of the genome? (iii)Which domains or parts of domains participate in the following: antigen binding; binding the T-cell receptor; and binding the T-cell co-receptor? (iv)Which domains are the most polymorphic?
B.Repeat this for an MHC class II molecule.

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