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Trisomy 21,or Down syndrome,occurs when there is a normal diploid chromosomal complement but one extra) chromosome 21.Although fertility is reduced in both sexes,females have higher fertility rates than males.Van Dyke et al.1995; Down Syndrome Research and Practice 32 : 65-69 summarize data involving children born of Down syndrome individuals.Assume that children are born to a female with Down syndrome and a normal 46- chromosome male.What proportion of the offspring would be expected to have Down syndrome?
Validity Error
A discrepancy or mistake that affects the accuracy or truthfulness of a test's results.
Content Validity
The extent to which a test or measure represents all facets of a given construct or domain.
Given Construct
A given construct refers to a specific concept or theoretical idea that is established and used as a basis for research or analysis.
Content Validity Ratio
A ratio of the number of raters who evaluate an item and the number of raters who deem an item to be an essential component of the construct being measured.
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