Colchicine Is an Alkaloid Derived from Plants

question 23

Multiple Choice

Colchicine is an alkaloid derived from plants.What is its effect on chromosome behavior?

• A)By blocking DNA replication,chromosomes fail to migrate to the poles at anaphase; thus,homologous chromosomes end up in the same nucleus.
• B)By blocking DNA replication,chromosomes do not undergo meiosis II and instead half the gametes are empty.
• C)By blocking DNA replication,chromosomes do not undergo meiosis I and instead all gametes suffer from aneuploidy.
• D)By interfering with spindle formation,replicated chromosomes fail to migrate to the poles at anaphase; thus,sister chromatids end up in the same nucleus.
• E)By interfering with spindle formation,replicated chromosomes fail to migrate to the poles at anaphase; thus,homologous chromosomes end up in the same nucleus.

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Definitions:

Valuation Allowance

A reserve created by a company to offset a portion of the deferred tax assets when it is more likely than not that some portion or all of the deferred tax assets will not be realized.

Business Combination

A business making an investment in another business by acquiring a controlling share, often greater than 50%, of the outstanding voting stock of another corporation by paying cash or exchanging stock.

Accrued Interest

Interest that has been incurred but not yet paid, reflecting the cost of borrowing or the earnings from lending money over a specific period.

Semiannual Interest

Interest on a loan or investment calculated and paid twice a year, typically at a fixed rate.