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Trisomy 21,or Down Syndrome,occurs When There Is a Normal Diploid

question 45

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Trisomy 21,or Down syndrome,occurs when there is a normal diploid chromosomal complement but one extra) chromosome 21.Although fertility is reduced in both sexes,females have higher fertility rates than males.Van Dyke et al.1995; Down Syndrome Research and Practice 32 : 65-69 summarize data involving children born of Down syndrome individuals.Assume that children are born to a female with Down syndrome and a normal 46- chromosome male.What proportion of the offspring would be expected to have Down syndrome?


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