Colchicine Is an Alkaloid Derived from Plants

question 23

Multiple Choice

Colchicine is an alkaloid derived from plants.What is its effect on chromosome behavior?

• A)By blocking DNA replication,chromosomes fail to migrate to the poles at anaphase; thus,homologous chromosomes end up in the same nucleus.
• B)By blocking DNA replication,chromosomes do not undergo meiosis II and instead half the gametes are empty.
• C)By blocking DNA replication,chromosomes do not undergo meiosis I and instead all gametes suffer from aneuploidy.
• D)By interfering with spindle formation,replicated chromosomes fail to migrate to the poles at anaphase; thus,sister chromatids end up in the same nucleus.
• E)By interfering with spindle formation,replicated chromosomes fail to migrate to the poles at anaphase; thus,homologous chromosomes end up in the same nucleus.

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