If an X- Linked Disorder Is Lethal to the Affected

question 45

Multiple Choice

If an X- linked disorder is lethal to the affected individual prior to the age at which one reaches reproductive maturation,the lethality will be expressed only in males.Why is this so?

• A)Because it's sex- limited inheritance,females do not demonstrate the phenotype.
• B)The only sources of the lethal allele in the population are heterozygous females who are "carriers" and do not express the disorder.
• C)At the cellular level,the protein will work less well in the male's cells.
• D)As it's a lethal allele,it will kill the homozygous recessive first.These are the males.
• E)This is not true.We will see the lethality in females as well.