In Sporadic Cases of Retinoblastoma,only Two Gene Mutations Are Thought

question 36

Multiple Choice

In sporadic cases of retinoblastoma,only two gene mutations are thought to be necessary in the same cell for a tumor to develop.This happens when an organism inherits a mutant allele and a wild- type allele forms the parents.When the wild- type allele is mutated,resulting in tumorigenesis,this process is called,_______ .

• A)gain of heterozygosity
• B)loss of heterozygosity
• C)recombination
• D)metastasizing
• E)attenuation

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