Consider the Genes IGF2 and H19 and the Imprinting Control

question 25

Essay

Consider the genes IGF2 and H19 and the imprinting control region ICR)between them.If the paternal ICR region was mutated in such a way that it could not be methylated but the maternal ICR was not mutated,how would that effect growth? In your explanation describe the expression of IGF2 and H19 from both the maternal and paternal alleles.

---

Definitions:

Expression

A combination of symbols that represents a mathematical concept or quantity.

Radical Expression

An expression that includes a radical sign, signifying the root of a number.

Simplify

To alter an expression into its simplest form by combining like terms, reducing fractions, or applying other algebraic rules.

Absolute Value

The length between a number and zero on a number line, disregarding its direction.