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Sickle- Cell Anemia Is Caused by a Mutation That Changes

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Essay

Sickle- cell anemia is caused by a mutation that changes the second nucleotide of the codon from GAG to GUG.This results in a change of the amino acid from glutamic acid to valine.If the mutation affected the third nucleotide of the codon and changed GAG to GAU then the amino acid would change from a glutamic acid to aspartic acid.Would you predict this change to have the same effect?


Definitions:

Significance Level

The probability threshold below which the null hypothesis is rejected in a statistical test, commonly denoted by alpha (α).

Sample Data

A subset of a population used to estimate or make inferences about the entire population.

Significance Level

The probability of rejecting the null hypothesis in a statistical test when it is actually true, commonly set thresholds include 0.05, 0.01.

Random Sample

A subset of individuals chosen from a larger set, where each individual has an equal chance of being selected.

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