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Patients with a relative contraindication for vasoconstrictors can receive epinephrine containing local anesthetic agents in the lowest possible dose,not to exceed the MRD of 0.04 mg per appointment,using the best technique.In general,there are only a few absolute contraindications to the use of vasoconstrictor,and in most situations limiting the amount of vasoconstrictor a patient can receive produces the benefits of vasoconstrictor use in local anesthesia without compromising the patient.
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