Two Parents Heterozygous for Cystic Fibrosis Have a Child with the Disease

question 20

Multiple Choice

Two parents heterozygous for cystic fibrosis have a child with the disease. The parents are expecting a second child. What is the probability that the second child will also have cystic fibrosis?

• A) 100% probability
• B) 75% probability
• C) 50% probability
• D) 25% probability
• E) 0% probability

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Definitions:

Wilcoxon Signed Rank Sum Test

A statistical test that doesn't rely on parameters to compare two matched groups, aiming to determine if there is a difference in their population mean ranks.

Normal Approximation

A technique in statistics where a binomial distribution is approximated using a normal distribution, applicable under certain conditions, such as a large sample size.

F-distribution

A probability distribution used in analysis of variance (ANOVA), especially relevant when comparing variances across different samples.

Kruskal-Wallis Test

A non-parametric statistical test that compares three or more independent samples to determine if at least one sample distribution stochastically dominates one other sample.