The FDA Recommends Genetic Testing of Which of the Following

question 8

Multiple Choice

The FDA recommends genetic testing of which of the following for patients prior to initiating abacavir due to a risk of potentially fatal multiorgan hypersensitivity in 6-10% of users?

• A) CYP2C19
• B) HLA-B*5701
• C) CYP2D6
• D) UGT1A1

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Definitions:

T-Distribution

A probability distribution that arises in the sampling distribution of sample means, especially useful when the sample size is small and the population variance is unknown.

Population Mean

The average value of all members of a defined set of people, objects, events, or values of interest.

T Distribution Table

A table used in statistics that shows the critical values of the t-distribution, aiding in hypothesis testing and confidence interval estimation.

Degrees Of Freedom

A concept in statistical analysis that represents the number of values in a calculation that are free to vary without violating any given constraints.