CD34 Enumeration Is Useful in Bone Marrow and Peripheral Blood

question 3

Multiple Choice

CD34 enumeration is useful in bone marrow and peripheral blood stem cell transplantation. For this enumeration, the EWGCCA recommendations include proper technique and interpretation of the flow cytometry analysis. Which of the following standards was recommended for proper acquisition of events?

• A) Include platelets and unlysed red blood cells and debris
• B) Include only CD34 dim staining populations
• C) Use bright fluorochrome conjugates of class II or III monoclonal antibodies that detect all glycoforms of CD34
• D) Acquire only 10 CD34 positive cells

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Definitions:

Receptor

A protein molecule that receives and responds to chemical signals, such as hormones or neurotransmitters, within the body.

Glial Cell

Non-neuronal cells in the central and peripheral nervous system that provide support and protection for neurons.

Epithelial Cell

Cells that line the surfaces of the body, including skin, blood vessels, and organs, serving as a barrier and interface with the environment.

Soma

In the context of biology, soma refers to the body of an organism as distinct from its reproductive cells; in other contexts, it can mean the cell body of a neuron.