A Sickle Solubility Test Is Requested STAT on a 45-Year-Old

question 43

Multiple Choice

A sickle solubility test is requested STAT on a 45-year-old patient who is to have surgery very soon. The technologist receives the sample and immediately takes the reagent out from the refrigerator and performs the test. It comes back positive. The surgery is postponed until hemoglobin electrophoresis is performed, and it shows a normal distribution of adult hemoglobins. What is the most likely reason for the discrepant result?

• A) There was a false positive on the sickle solubility test because of the cold reagent.
• B) The hemoglobin electrophoresis findings need to be confirmed on acid gel.
• C) There was a false negative on the sickle solubility test because of inadequate mixing.
• D) The wrong patient was drawn.

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Definitions:

Statistical Test

is a mathematical procedure applied to data in order to determine the significance of relationships or differences among variables.

Sample Size

Refers to the number of observations or units included in a study, affecting the study's power and generalizability.

Target Population

The specific group of individuals to whom a particular research study, policy, or intervention is directed.

Effect Size

Effect size is a quantitative measure of the magnitude of the difference between groups or the strength of a relationship between variables in a statistical analysis.