Large Cells with Abundant, Intensely Basophilic Cytoplasm with Prominent Cytoplasmic

question 30

Multiple Choice

Large cells with abundant, intensely basophilic cytoplasm with prominent cytoplasmic vacuolization are identified on a peripheral smear. Multiple basophilic nucleoli are present. A starry sky appearance is seen with fields of basophilic leukemic blasts with benign macrophages that have ingested tumor cells. What leukemia should be suspected with this morphology?

• A) Acute undifferentiated leukemia
• B) Acute lymphoblastic leukemia-Burkitt-type
• C) Acute leukemia with lineage heterogeneity
• D) Precursor T-cell leukemia

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