Explain How a Somatic Mutation in the PIGA Gene Leads

question 21

Essay

Explain how a somatic mutation in the PIGA gene leads to PNH.

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Definitions:

Restatement (Second)

A series of legal treatises that summarize the common law in several areas, serving as authoritative guides but not binding law.

Registered Mail

A postal service offering added security and tracking for mailings, requiring the signature of the recipient upon delivery.

Traditional Contract Law

The body of law governing agreements between parties, requiring elements such as offer, acceptance, consideration, and mutual consent for enforceability.

Counteroffer

A proposal made in response to an offer, which effectively rejects the original offer and proposes new terms for an agreement.