Mary, a 7-Year-Old, Was Admitted to the Hospital After Experiencing

question 4

Multiple Choice

Mary, a 7-year-old, was admitted to the hospital after experiencing severe anemia following a respiratory infection. Her father has a history of RBC membrane abnormality and recently underwent a splenectomy to help alleviate the problem. Upon examination, it was revealed that Mary had hepatosplenomegaly and slight bruising on her forearms. A CBC was ordered, with the following results: HGB 10.8 g/dL
HCT 29.2%
WBC 11 × 10⁹/L
RBC 3.8 × 10¹²/L
MCV 77 fl
MCH 28 pg
MCHC 37%
PLT 275 × 10⁹/L
Peripheral smear: moderate polychromasia and spherocytes
Which of the following is most consistent with a presumptive diagnosis in this case?

• A) PNH
• B) HS
• C) DHS
• D) HE

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Definitions:

New England Colonists

The early settlers of the northeastern region of what is now the United States during the 17th and early 18th centuries, many of whom were seeking religious freedom.

English Civil War

A series of armed conflicts and political machinations between Parliamentarians ("Roundheads") and Royalists ("Cavaliers") from 1642 to 1651 in England, leading to the trial and execution of Charles I, and the establishment of a Commonwealth.

Legal Standing

The right of an individual or entity to bring a lawsuit to court based on their stake in the outcome of a controversy needing judicial resolution.

King Philip's War

A conflict between American Indian inhabitants of present-day New England and English colonists and their Indian allies in 1675–1678.