Propose a mechanism for the following transformation. 
Definitions:
Cell Fractionation
The technique used to separate the components of cells by subjecting them to centrifugal force. See differential centrifugation and density gradient centrifugation.
Biochemical Techniques
methods used in biology to study the structure and function of macromolecules like proteins and nucleic acids.
Physical Separation
The process of establishing a distance or barrier between objects or individuals, often for safety, privacy, or organizational purposes.
Smooth ER
The smooth endoplasmic reticulum is a membrane-enclosed organelle found in eukaryotic cells, involved in lipid synthesis, detoxification, and calcium ion storage.
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