Amino Acid Synthesis Is Possible by All Except One of the Pathways

question 18

Multiple Choice

Amino acid synthesis is possible by all except one of the pathways listed.Which is not a synthetic pathway for amino acids?

• A)Amination of malonic ester followed by hydrolysis and decarboxylation
• B)Nucleophilic addition of NH₃ to an aldehyde followed by addition of cyanide to the imine,and,finally,hydrolysis
• C)S_N2 reaction using an a-halo carboxylic acid with ammonia as the nucleophile
• D)Reaction of NH₄Cl and NaCN with an aldehyde followed by an acidic work-up